diff --git a/modules/hal_nordic/nrfx/Kconfig b/modules/hal_nordic/nrfx/Kconfig
index 65894d48712..83ce3f157cc 100644
--- a/modules/hal_nordic/nrfx/Kconfig
+++ b/modules/hal_nordic/nrfx/Kconfig
@@ -169,6 +169,16 @@ config NRFX_PDM0
 	depends on $(dt_nodelabel_has_compat,pdm0,$(DT_COMPAT_NORDIC_NRF_PDM))
 	select NRFX_PDM
 
+config NRFX_PDM20
+	bool "PDM20 driver instance"
+	depends on $(dt_nodelabel_has_compat,pdm20,$(DT_COMPAT_NORDIC_NRF_PDM))
+	select NRFX_PDM
+
+config NRFX_PDM21
+	bool "PDM21 driver instance"
+	depends on $(dt_nodelabel_has_compat,pdm21,$(DT_COMPAT_NORDIC_NRF_PDM))
+	select NRFX_PDM
+
 config NRFX_POWER
 	bool "POWER driver"
 	depends on $(dt_has_compat,$(DT_COMPAT_NORDIC_NRF_POWER))
diff --git a/modules/hal_nordic/nrfx/nrfx_config.h b/modules/hal_nordic/nrfx/nrfx_config.h
index 56e59879563..9b664c24374 100644
--- a/modules/hal_nordic/nrfx/nrfx_config.h
+++ b/modules/hal_nordic/nrfx/nrfx_config.h
@@ -209,11 +209,17 @@
 #ifdef CONFIG_NRFX_PDM
 #define NRFX_PDM_ENABLED 1
 #endif
+#ifdef CONFIG_NRFX_PDM_LOG
+#define NRFX_PDM_CONFIG_LOG_ENABLED 1
+#endif
 #ifdef CONFIG_NRFX_PDM0
 #define NRFX_PDM0_ENABLED 1
 #endif
-#ifdef CONFIG_NRFX_PDM_LOG
-#define NRFX_PDM_CONFIG_LOG_ENABLED 1
+#ifdef CONFIG_NRFX_PDM20
+#define NRFX_PDM20_ENABLED 1
+#endif
+#ifdef CONFIG_NRFX_PDM21
+#define NRFX_PDM21_ENABLED 1
 #endif
 
 #ifdef CONFIG_NRFX_POWER
diff --git a/modules/hal_nordic/nrfx/nrfx_config_nrf5340_application.h b/modules/hal_nordic/nrfx/nrfx_config_nrf5340_application.h
index a5dbcaa3db8..ab04db03f15 100644
--- a/modules/hal_nordic/nrfx/nrfx_config_nrf5340_application.h
+++ b/modules/hal_nordic/nrfx/nrfx_config_nrf5340_application.h
@@ -596,6 +596,15 @@
 #define NRFX_PDM_CONFIG_LOG_LEVEL 3
 #endif
 
+/**
+ * @brief NRFX_PDM0_ENABLED
+ *
+ * Boolean. Accepted values 0 and 1.
+ */
+#ifndef NRFX_PDM0_ENABLED
+#define NRFX_PDM0_ENABLED 0
+#endif
+
 /**
  * @brief NRFX_POWER_ENABLED
  *
diff --git a/soc/nordic/common/Kconfig.peripherals b/soc/nordic/common/Kconfig.peripherals
index 57c90b05ef7..8ba97b225b9 100644
--- a/soc/nordic/common/Kconfig.peripherals
+++ b/soc/nordic/common/Kconfig.peripherals
@@ -129,6 +129,12 @@ config HAS_HW_NRF_OSCILLATORS
 config HAS_HW_NRF_PDM0
 	def_bool $(dt_nodelabel_enabled_with_compat,pdm0,$(DT_COMPAT_NORDIC_NRF_PDM))
 
+config HAS_HW_NRF_PDM20
+	def_bool $(dt_nodelabel_enabled_with_compat,pdm20,$(DT_COMPAT_NORDIC_NRF_PDM))
+
+config HAS_HW_NRF_PDM21
+	def_bool $(dt_nodelabel_enabled_with_compat,pdm21,$(DT_COMPAT_NORDIC_NRF_PDM))
+
 config HAS_HW_NRF_POWER
 	def_bool $(dt_compat_enabled,$(DT_COMPAT_NORDIC_NRF_POWER))
 
diff --git a/soc/nordic/validate_base_addresses.c b/soc/nordic/validate_base_addresses.c
index 84d773159bc..07ae94a233b 100644
--- a/soc/nordic/validate_base_addresses.c
+++ b/soc/nordic/validate_base_addresses.c
@@ -222,6 +222,8 @@ CHECK_DT_REG(nfct, NRF_NFCT);
 CHECK_DT_REG(nrf_mpu, NRF_MPU);
 CHECK_DT_REG(oscillators, NRF_OSCILLATORS);
 CHECK_DT_REG(pdm0, NRF_PDM0);
+CHECK_DT_REG(pdm20, NRF_PDM20);
+CHECK_DT_REG(pdm21, NRF_PDM21);
 CHECK_DT_REG(power, NRF_POWER);
 CHECK_DT_REG(ppi, NRF_PPI);
 CHECK_DT_REG(pwm0, NRF_PWM0);