diff --git a/drivers/spi/spi_xmc4xxx.c b/drivers/spi/spi_xmc4xxx.c
index d6aa60a527f..1706572bddb 100644
--- a/drivers/spi/spi_xmc4xxx.c
+++ b/drivers/spi/spi_xmc4xxx.c
@@ -468,7 +468,9 @@ static int spi_xmc4xxx_transceive_dma(const struct device *dev, const struct spi
 		spi_context_cs_control(ctx, false);
 	}
 
+#if defined(CONFIG_SPI_XMC4XXX_INTERRUPT)
 	irq_enable(config->irq_num_rx);
+#endif
 	spi_context_release(ctx, ret);
 
 	return ret;
diff --git a/tests/drivers/spi/spi_loopback/boards/xmc45_relax_kit.conf b/tests/drivers/spi/spi_loopback/boards/xmc45_relax_kit.conf
index d066213b5da..3f96b399e0e 100644
--- a/tests/drivers/spi/spi_loopback/boards/xmc45_relax_kit.conf
+++ b/tests/drivers/spi/spi_loopback/boards/xmc45_relax_kit.conf
@@ -1,3 +1,2 @@
-CONFIG_SPI_XMC4XXX_INTERRUPT=y
 CONFIG_SPI_XMC4XXX_DMA=y
 CONFIG_SPI_LOOPBACK_MODE_LOOP=y